全業績リスト (原 弘真)

発表論文 (25編)　★ 博士論文を構成した主論文

  1. S. Hochi, H. Abdalla, H. Hara, M. Shimoda, H. Morita, M. Kuwayama, M. Hirabayashi. (2010) Stimulatory effect of Rho-associated coiled-coil kinase (ROCK) inhibitor on revivability of in vitro-produced bovine blastocysts after vitrification. Theriogenology, 73 (8), 1139-1145.
  2. H. Abdalla, M. Shimoda, H. Hara, H. Morita, M. Kuwayama, M. Hirabayashi, S. Hochi. (2010) Vitrification of ICSI- and IVF-derived bovine blastocysts by minimum volume cooling procedure: effect of developmental stage and age. Theriogenology, 74 (6), 1028-1035. ★
  3. H. Hara, H. Abdalla, H. Morita, M. Kuwayama, M. Hirabayashi, S. Hochi. (2011) Procedure for bovine ICSI, not sperm freeze-drying, impairs the function of the microtubule-organizing center. J. Reprod. Dev., 57 (3), 428-432. (カバーアートに採用) ★
  4. H. Hara, I-S. Hwang, N. Kagawa, M. Kuwayama, M. Hirabayashi, S. Hochi. (2012) High incidence of multiple aster formation in vitrified-warmed bovine oocytes after in vitro fertilization. Theriogenology, 77 (5), 908-915.
  5. I-S. Hwang, H. Hara, H-J. Chung, M. Hirabayashi, S. Hochi. (2013) Rescue of vitrified-warmed bovine oocytes with Rho-associated coiled-coil kinase inhibitor. Biol. Reprod., 89 (2), 26.
  6. M. Hirabayashi, T. Goto, C. Tamura, M. Sanbo, H. Hara, M. Kato-Itoh, H. Sato, T. Kobayashi, H. Nakauchi, S. Hochi. (2014) Derivation of embryonic stem cell lines from parthenogenetically developing rat blastocysts. Stem Cells Dev., 23 (2), 107-114.
  7. M. Hirabayashi, T. Goto, C. Tamura, M. Sanbo, H. Hara, S. Hochi. (2014) Effect of leukemia inhibitory factor and forskolin on establishment of rat embryonic stem cell lines. J. Reprod. Dev., 60 (1), 78-82.
  8. H. Hara, M. Tagiri, I-S. Hwang, M. Takahashi, M. Hirabayashi, S. Hochi. (2014) Adverse effect of cake collapse on the functional integrity of freeze-dried bull spermatozoa. Cryobiology, 68 (3), 354-360. ★
  9. H. Hara, I. Yamane, I. Noto, N. Kagawa, M. Kuwayama, M. Hirabayashi, S. Hochi. (2014) Microtubule assembly and in vitro development of bovine oocytes with increased intracellular glutathione level prior to vitrification and in vitro fertilization. Zygote, 22 (4), 476-482. ★
  10. I. Yashiro, M. Tagiri, H. Ogawa, K. Tashima, S. Takashima, H. Hara, M. Hirabayashi, S. Hochi. (2015) High revivability of vitrified-warmed bovine mature oocytes after recovery culture with α-tocopherol. Reproduction, 149 (4), 347-355.
  11. T. Goto, T. Kobayashi, H. Hara, M. Sanbo, S. Hochi, H. Nakauchi, M. Hirabayashi. (2015) Knock-in of a histone H2B-tdTomato reporter into the Rosa26 locus allows visualization of cell nuclei in rats. Mol. Reprod. Dev., 82 (12), 916-917.
  12. H. Hara, M. Tagiri, M. Hirabayashi, S. Hochi. (2016) Multiple aster formation is frequently observed in bovine oocytes retrieved from 1 day-stored ovaries. Zygote, 24 (1), 115-120.
  13. H. Hara, T. Goto, A. Takizawa, H.J. Jacob, M. Sanbo, T. Kobayashi, H. Nakauchi, S. Hochi, M. Hirabayashi. (2016) Rat blastocysts from nuclear injection and time-lagged enucleation and their commitment to embryonic stem cells. Cell. Reprogram., 18 (2), 108-115.
  14. T. Goto, H. Hara, H. Nakauchi, S. Hochi, M. Hirabayashi. (2016) Hypomorphic phenotype of Foxn1 gene-modified rats by CRISPR/Cas9 system. Transgenic Res., 25 (4), 533-544.
  15. T. Yamaguchi, H. Sato, M. Kato-Itoh, T. Goto, H. Hara, M. Sanbo, N. Mizuno, T. Kobayashi, A. Yanagida, A. Umino, Y. Ota, S. Hamanaka, H. Masaki, S.T. Rashid, M. Hirabayashi, H. Nakauchi. (2017) Interspecies organogenesis generates autologous functional islets. Nature, 542 (7640), 191-196.
  16. M. Hirabayashi, H. Hara, T. Goto, A. Takizawa, M.R. Dwinell, T. Yamanaka, S. Hochi, H. Nakauchi. (2017) Haploid embryonic stem cell lines derived from androgenetic and parthenogenetic rat blastocysts. J. Reprod. Dev., 63 (6), 611-616.
  17. H. Hara, H. Shibata, K. Nakano, T. Abe, H. Uosaki, T. Ohnuki, S. Hishikawa, S. Kunita, M. Watanabe, O. Nureki, H. Nagashima, Y. Hanazono. (2018) Production and rearing of germ-free X-SCID pigs. Exp. Anim., 67 (2), 139-146. (カバーアートに採用)
  18. T. Yamaguchi, H. Sato, T. Kobayashi, M. Kato-Itoh, T. Goto, H. Hara, N. Mizuno, A. Yanagida, A. Umino, S. Hamanaka, F. Suchy, H. Masaki, Y. Ota, M. Hirabayashi, H. Nakauchi. (2018) An interspecies barrier to tetraploid complementation and chimera formation. Sci. Rep., 8, 15289.
  19. T. Goto, H. Hara, M. Sanbo, H. Masaki, H. Sato, T. Yamaguchi, S. Hochi, T. Kobayashi, H. Nakauchi, M. Hirabayashi. (2019) Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats. Nat. Commun., 10 (1), 451.
  20. S. Byambaa, H. Uosaki, H. Hara, Y. Nagao, T. Abe, H. Shibata, O. Nureki, t. Ohmori, Y. Hanazono. (2020) Generation of novel Il2rg-knockout mice with clustered regularly interspaced short palindromic repeats (CRISPR) and Cas9. Exp. Anim., 69 (2), 189-198.e8
  21. T. Abe, H. Uosaki, H. Shibata, H. Hara, B. Sarentonglaga, Y. Nagao, Y. Hanazono. (2021) Fetal sheep support the development of hematopoietic cells in vivo from human induced pluripotent stem cells. Exp. Hematol., 95, 46-57.
  22. S. Byambaa, H. Uosaki, T. Ohmori, H. Hara, H. Endo, O. Nureki, Y. Hanazono. (2021) Non-viral ex vivo genome-editing in mouse bona fide hematopoietic stem cells with CRISPR/Cas9. Mol. Ther. Methods Clin. Dev., 20, 451-462.
  23. Y. Kazuki, F.J. Gao, M. Yamakawa, M. Hirabayashi, K. Kazuki, N. Kajitani, S. Miyagawa-Tomita, S. Abe, M. Sanbo, H. Hara, H. Kuniishi, S. Ichisaka, Y. Hata, M. Koshima, H. Takayama, S. Tokehara, Y. Nakayama, M. Hiratsuka, Y. Iida, S. Matsukura, N. Noda, Y. Li, A.J. Moyer, B. Cheng, N. Singh, J.T. Richtsmeier, M. Oshimura, R.H. Reeves. (2022) A transchromosomic rat model with human chromosome 21 shows robust Down syndrome features. Am. J. Hum. Genet., 109, 1-17.
  24. F. Tanihara, M. Hirata, Z Namula, M. Wittayarat, L.T.K. Do, Q. Lin, K. Takebayashi, H. Hara, M. Nagahara, T. Otoi. (2023) GHR-mutant pig derived from domestic pig and microminipig hybrid zygotes using CRISPR/Cas9 system. Mol. Biol. Rep., 50 (6), 5049-5057.
  25. M. Minegishi, T. Kuchimaru, K. Nishikawa, T. Isagawa, S. Iwano, K. Iida, H. Hara, S. Miura, M. Sato, S. Watanabe, A. Shiomi, Y. Mabuchi, H. Hamana, H. Kishi, T. Sato, D. Sawaki, S. Sato, Y. Hanazono, A. Suzuki, T. Kohro, T. Kadonosono, T. Shimogori, A. Miyawaki, N. Takeda, H. Shintaku, S. Kizaka-Kondoh, S. Nishimura, S. (2023) Secretory GFP reconstitution labeling of neighboring cells interrogates cell-cell interactions in metastatic niches. Nat. Commun., 14 (1), 8031.

著書 (2編)

  1. T. Anzai, H. Hara, C. Nawin, T. Sadahiro, M. Ieda, Y. Hanazono, H. Uosaki. (2021) Generation of efficient knock-in mouse and human pluripotent stem cells using CRISPR-Cas9. Y. Yoshida ed.「Pluripotent Stem-Cell Derived Cardiomyocytes (Humana Press)」Methods Mol. Biol., Series-2320, 247-259.
  2. H. Hara, N. Munkh-Erdene, S. Byambaa, Y. Hanazono. (2023) Nonviral ex vivo genome editing in mouse bona fide hematopoietic stem cells with CRISPR-Cas9. I. Hatada ed.「Genome Editing in Animals (Humana Press)」Methods Mol. Biol., Series-2637, 213-221.

総説 (1編)

  1. S. Hochi, H. Abdalla, H. Hara, M. Hirabayashi. (2011) Challenging endeavour for preservation of freeze-dried mammalian spermatozoa. J. Reprod. Dev., 57 (5), 557-563.


　　　　　
　　　カバーアート採用誌表紙 (左: J. Reprod. Dev. 2011, 右: Exp. Anim. 2018)