全業績リスト (原 弘真)

発表論文 (25編)　★ 博士論文を構成した主論文

  1. S. Hochi, H. Abdalla, H. Hara, M. Shimoda, H. Morita, M. Kuwayama, M. Hirabayashi. (2010) Stimulatory effect of Rho-associated coiled-coil kinase (ROCK) inhibitor on revivability of in vitro-produced bovine blastocysts after vitrification. Theriogenology, 73 (8), 1139-1145.
  2. H. Abdalla, M. Shimoda, H. Hara, H. Morita, M. Kuwayama, M. Hirabayashi, S. Hochi. (2010) Vitrification of ICSI- and IVF-derived bovine blastocysts by minimum volume cooling procedure: effect of developmental stage and age. Theriogenology, 74 (6), 1028-1035. ★
  3. H. Hara, H. Abdalla, H. Morita, M. Kuwayama, M. Hirabayashi, S. Hochi. (2011) Procedure for bovine ICSI, not sperm freeze-drying, impairs the function of the microtubule-organizing center. J. Reprod. Dev., 57 (3), 428-432. (カバーアートに採用) ★
  4. H. Hara, I-S. Hwang, N. Kagawa, M. Kuwayama, M. Hirabayashi, S. Hochi. (2012) High incidence of multiple aster formation in vitrified-warmed bovine oocytes after in vitro fertilization. Theriogenology, 77 (5), 908-915.
  5. I-S. Hwang, H. Hara, H-J. Chung, M. Hirabayashi, S. Hochi. (2013) Rescue of vitrified-warmed bovine oocytes with Rho-associated coiled-coil kinase inhibitor. Biol. Reprod., 89 (2), 26 1-6.
  6. M. Hirabayashi, T. Goto, C. Tamura, M. Sanbo, H. Hara, M. Kato-Itoh, H. Sato, T. Kobayashi, H. Nakauchi, S. Hochi. (2014) Derivation of embryonic stem cell lines from parthenogenetically developing rat blastocysts. Stem Cells Dev., 23 (2), 107-114.
  7. M. Hirabayashi, T. Goto, C. Tamura, M. Sanbo, H. Hara, S. Hochi. (2014) Effect of leukemia inhibitory factor and forskolin on establishment of rat embryonic stem cell lines. J. Reprod. Dev., 60 (1), 78-82.
  8. H. Hara, M. Tagiri, I-S. Hwang, M. Takahashi, M. Hirabayashi, S. Hochi. (2014) Adverse effect of cake collapse on the functional integrity of freeze-dried bull spermatozoa. Cryobiology, 68 (3), 354-360. ★
  9. H. Hara, I. Yamane, I. Noto, N. Kagawa, M. Kuwayama, M. Hirabayashi, S. Hochi. (2014) Microtubule assembly and in vitro development of bovine oocytes with increased intracellular glutathione level prior to vitrification and in vitro fertilization. Zygote, 22 (4), 476-482. ★
  10. I. Yashiro, M. Tagiri, H. Ogawa, K. Tashima, S. Takashima, H. Hara, M. Hirabayashi, S. Hochi. (2015) High revivability of vitrified-warmed bovine mature oocytes after recovery culture with α-tocopherol. Reproduction, 149 (4), 347-355.
  11. T. Goto, T. Kobayashi, H. Hara, M. Sanbo, S. Hochi, H. Nakauchi, M. Hirabayashi. (2015) Knock-in of a histone H2B-tdTomato reporter into the Rosa26 locus allows visualization of cell nuclei in rats. Mol. Reprod. Dev., 82 (12), 916-917.
  12. H. Hara, M. Tagiri, M. Hirabayashi, S. Hochi. (2016) Multiple aster formation is frequently observed in bovine oocytes retrieved from 1 day-stored ovaries. Zygote, 24 (1), 115-120.
  13. H. Hara, T. Goto, A. Takizawa, H.J. Jacob, M. Sanbo, T. Kobayashi, H. Nakauchi, S. Hochi, M. Hirabayashi. (2016) Rat blastocysts from nuclear injection and time-lagged enucleation and their commitment to embryonic stem cells. Cell. Reprogram., 18 (2), 108-115.
  14. T. Goto, H. Hara, H. Nakauchi, S. Hochi, M. Hirabayashi. (2016) Hypomorphic phenotype of Foxn1 gene-modified rats by CRISPR/Cas9 system. Transgenic Res., 25 (4), 533-544.
  15. T. Yamaguchi, H. Sato, M. Kato-Itoh, T. Goto, H. Hara, M. Sanbo, N. Mizuno, T. Kobayashi, A. Yanagida, A. Umino, Y. Ota, S. Hamanaka, H. Masaki, S.T. Rashid, M. Hirabayashi, H. Nakauchi. (2017) Interspecies organogenesis generates autologous functional islets. Nature, 542 (7640), 191-196.
  16. M. Hirabayashi, H. Hara, T. Goto, A. Takizawa, M.R. Dwinell, T. Yamanaka, S. Hochi, H. Nakauchi. (2017) Haploid embryonic stem cell lines derived from androgenetic and parthenogenetic rat blastocysts. J. Reprod. Dev., 63 (6), 611-616.
  17. H. Hara, H. Shibata, K. Nakano, T. Abe, H. Uosaki, T. Ohnuki, S. Hishikawa, S. Kunita, M. Watanabe, O. Nureki, H. Nagashima, Y. Hanazono. (2018) Production and rearing of germ-free X-SCID pigs. Exp. Anim., 67 (2), 139-146. (カバーアートに採用)
  18. T. Yamaguchi, H. Sato, T. Kobayashi, M. Kato-Itoh, T. Goto, H. Hara, N. Mizuno, A. Yanagida, A. Umino, S. Hamanaka, F. Suchy, H. Masaki, Y. Ota, M. Hirabayashi, H. Nakauchi. (2018) An interspecies barrier to tetraploid complementation and chimera formation. Sci. Rep., 8, 15289 1-10.
  19. T. Goto, H. Hara, M. Sanbo, H. Masaki, H. Sato, T. Yamaguchi, S. Hochi, T. Kobayashi, H. Nakauchi, M. Hirabayashi. (2019) Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats. Nat. Commun., 10 (1), 451 1-9.
  20. S. Byambaa, H. Uosaki, H. Hara, Y. Nagao, T. Abe, H. Shibata, O. Nureki, t. Ohmori, Y. Hanazono. (2020) Generation of novel Il2rg-knockout mice with clustered regularly interspaced short palindromic repeats (CRISPR) and Cas9. Exp. Anim., 69 (2), 189-198.e8
  21. T. Abe, H. Uosaki, H. Shibata, H. Hara, B. Sarentonglaga, Y. Nagao, Y. Hanazono. (2021) Fetal sheep support the development of hematopoietic cells in vivo from human induced pluripotent stem cells. Exp. Hematol., 95, 46-57.
  22. S. Byambaa, H. Uosaki, T. Ohmori, H. Hara, H. Endo, O. Nureki, Y. Hanazono. (2021) Non-viral ex vivo genome-editing in mouse bona fide hematopoietic stem cells with CRISPR/Cas9. Mol. Ther. Methods Clin. Dev., 20, 451-462.
  23. Y. Kazuki, F.J. Gao, M. Yamakawa, M. Hirabayashi, K. Kazuki, N. Kajitani, S. Miyagawa-Tomita, S. Abe, M. Sanbo, H. Hara, H. Kuniishi, S. Ichisaka, Y. Hata, M. Koshima, H. Takayama, S. Tokehara, Y. Nakayama, M. Hiratsuka, Y. Iida, S. Matsukura, N. Noda, Y. Li, A.J. Moyer, B. Cheng, N. Singh, J.T. Richtsmeier, M. Oshimura, R.H. Reeves. (2022) A transchromosomic rat model with human chromosome 21 shows robust Down syndrome features. Am. J. Hum. Genet., 109, 1-17.
  24. F. Tanihara, M. Hirata, Z Namula, M. Wittayarat, L.T.K. Do, Q. Lin, K. Takebayashi, H. Hara, M. Nagahara, T. Otoi. (2023) GHR-mutant pig derived from domestic pig and microminipig hybrid zygotes using CRISPR/Cas9 system. Mol. Biol. Rep., 50 (6), 5049-5057.
  25. M. Minegishi, T. Kuchimaru, K. Nishikawa, T. Isagawa, S. Iwano, K. Iida, H. Hara, S. Miura, M. Sato, S. Watanabe, A. Shiomi, Y. Mabuchi, H. Hamana, H. Kishi, T. Sato, D. Sawaki, S. Sato, Y. Hanazono, A. Suzuki, T. Kohro, T. Kadonosono, T. Shimogori, A. Miyawaki, N. Takeda, H. Shintaku, S. Kizaka-Kondoh, S. Nishimura, S. (2024) Secretory GFP reconstitution labeling of neighboring cells interrogates cell-cell interactions in metastatic niches. Nat. Commun., 14 (1), 8031 1-12.

著書 (2編)

  1. T. Anzai, H. Hara, C. Nawin, T. Sadahiro, M. Ieda, Y. Hanazono, H. Uosaki. (2021) Generation of efficient knock-in mouse and human pluripotent stem cells using CRISPR-Cas9. Y. Yoshida ed.「Pluripotent Stem-Cell Derived Cardiomyocytes (Humana Press)」Methods Mol. Biol., Series-2320, 247-259.
  2. H. Hara, N. Munkh-Erdene, S. Byambaa, Y. Hanazono. (2023) Nonviral ex vivo genome editing in mouse bona fide hematopoietic stem cells with CRISPR-Cas9. I. Hatada ed.「Genome Editing in Animals (Humana Press)」Methods Mol. Biol., Series-2637, 213-221.

総説 (1編)

  1. S. Hochi, H. Abdalla, H. Hara, M. Hirabayashi. (2011) Challenging endeavour for preservation of freeze-dried mammalian spermatozoa. J. Reprod. Dev., 57 (5), 557-563.


　　　　　
　　　カバーアート採用誌表紙 (左: J. Reprod. Dev. 2011, 右: Exp. Anim. 2018)