発表論文 (54編)　★ 博士論文を構成した主論文

1. H-G. Lee, H-C. Lee, H-J. Chung, I-S. Hwang, M-S. Choi, S-J. Byun, M-J. Kim, J-S. Woo, W-K. Chang, P. Lee, H-T. Lee, J-K. Park. (2008) Study on the reproductive function in transgenic pig harboring human erythropoietin (hEPO) gene. Reprod. Dev. Biol., 32 (2), 117-121.
2. H-G. Lee, H-C. Lee, S. Kim, P. Lee, H-J. Chung, Y-K. Lee, J-H. Han, I-S. Hwang, J-I. Yoo, Y-K. Kim, H-T. Kim, H-T. Lee, W-K. Chang, J-K. Park. (2009) Production of recombinant human von Willebrand factor in the milk of transgenic pigs. J. Reprod. Dev., 55 (5), 484-490.
3. S. Byun, S. Kim, K-W. Kim, J. Kim, I-S. Hwang, H. Chung, I. Kan, I-S. Jeon, W-K. Chang, S-B. Park, J. Yoo. (2011) Oviduct-specific enhanced green fluorescent protein expression in transgenic chickens. Biosci. Biotech. Biochem., 75 (4), 646-649.
4. I-S. Hwang, S. Kim, S. Byun, K-W. Kim, H. Chung, J-J. Park, K. Gobianand, J-K. Park, J. Yoo. (2012) The effect of horse serum on in vitro development of porcine parthenogenetic embryos. Reprod. Biol., 12 (1), 25-39.
5. H. Hara, I-S. Hwang, N. Kagawa, M. Kuwayama, M. Hirabayashi, S. Hochi. (2012) High incidence of multiple aster formation in vitrified-warmed bovine oocytes after in vitro fertilization. Theriogenology, 77 (5), 908-915. ★
6. M-S. Choi, M-R. Shim, M-Y. Oh, K-W. Kim, H-C. Lee, B-C. Yang, H. Chung, J-H. Kim, H-T. Lee, I-S. Hwang, S. Hochi, Y-T. Heo, N-H. Kim, S-J. Uhm, J-K. Park, W-K. Chang, H-J. Chung. (2012) Proteins associated with reproductive disorders in testes of human erythropoietin gene-harboring transgenic boars. Theriogenology, 78 (5), 1020-1029.
7. I-S. Hwang, H. Hara, H-J. Chung, M. Hirabayashi, S. Hochi. (2013) Rescue of vitrified-warmed bovine oocytes with Rho-associated coiled-coil kinase inhibitor. Biol. Reprod., 89 (2), 26. ★
8. H. Hara, M. Tagiri, I-S. Hwang, M. Takahashi, M. Hirabayashi, S. Hochi. (2014) Adverse effect of cake collapse on the functional integrity of freeze-dried bull spermatozoa. Cryobiology, 68 (3), 354-360.
9. J-H. Yeo, I-S. Hwang, J-K. Park, D-J. Kwon, S. Im, E-W. Park, J-W. Lee, C-K. Park, S. Hwang. (2014) Transgenic efficiency of FoxN1-targeted pig parthenogenetic embryos. J. Emb. Trans., 29 (4), 339-344.
10. I-S. Hwang, D-J. Kwon, K. Oh, S-A. Ock, H-J. Chung, I-C. Cho, J-W. Lee, G-S. Im, S. Hwang. (2015) Production of cloned Korean native pig by somatic cell nuclear transfer. Dev. Reprod., 19 (2), 79-84.
11. D-J. Kwon, I-S. Hwang, T-U. Kwak, K-B. Oh, S. Ock, H-J. Chung, G-S. Im, S. Hwang. (2015) Effect of stem cell-derived conditioned medium on the in vitro maturation and embryonic development of parthenogenetic embryos in pigs. Reprod. Dev. Biol., 39 (3), 89-95.
12. I-S. Hwang, D-J. Kwon, T-U. Kwak, K-B. Oh, S. Ock, H-J. Chung, G-S. Im, S. Hwang. (2015) Characterization of α-gal epitope in cells and tissues from homozygous α-1,3-galactosyltransferase knockout pigs. Reprod. Dev. Biol., 39 (4), 127-132.
13. H-J. Chung, N-R. Son, J-H. Han, C-G. Park, K-W. Kim, M-R. Park, I-S. Hwang, J-K. Park, G-S. Im. (2015) Prolonged expression of exogenous GFP gene in the porcine embryos generated by intracytoplasmic sperm injection-mediated gene transfer. J. Emb. Trans., 30 (3), 225-228.
14. I-S. Hwang, D-J. Kwon, G-S. Im, K. Tashima, S. Hochi, S. Hwang. (2016) High incidence of polyspermic fertilization in bovine oocytes matured in vitro after cryotop vitrification. CryoLetters, 37 (1), 27-33.
15. I-S. Hwang, D-J. Kwon, T-U. Kwak, J-W. Lee, G-S. Im, S. Hwang. (2016) Improved survival and developmental rates in vitrified-warmed pig oocytes after recovery culture with coenzyme Q10. CryoLetters, 37 (1), 59-67.
16. D-J. Kwon, I-S. Hwang, H-R. Kim, Y-R. Kim, K. Oh, S. Ock, G-S. Im, J-W. Lee, S. Hwang. (2016) Aberrant methylation of Meg3 in alpha1,3-galactosyltransferase knockout pig induced pluripotent stem cells. Anim. Cells Sys., 20 (3), 130-139.
17. I-S. Hwang, D-J. Kwon, T-U. Kwak, J-Y. Lee, N-W. Hyung, H. Yang, K-B. Oh, S. Ock, E-W. Park, G-S. Im, S. Hwang. (2016) Effect of a short-term in vitro exposure time on the production of in vitro produced piglets. J. Emb. Trans., 31 (2), 117-121.
18. W-S. Sun, J-L. Chun, J-T. Do, D-H. Kim, J-S. Ahn, M-K. Kim, I-S. Hwang, D-J. Kwon, S-S. Hwang, J-W. Lee. (2016) Construction of a dual-fluorescence reporter system to monitor the dynamic progression of pluripotent cell differentiation. Stem Cell Int., 2016, ID 1390284.
19. D-J. Kwon, D-H. Kim, I-S. Hwang, D-E. Kim, H-J. Kim, J-S. Kim, K. Lee, G-S. Im, J-W. Lee, S. Hwang. (2017) Generation of α-1,3-galactosyltransferase knocked-out transgenic cloned pigs with knocked-in five human genes. Transgenic Res., 26 (1), 153-163.
20. D-J. Kwon, I-S. Hwang, T-U. Kwak, H. Yang, M-R. Park, S-A. Ock, K. Oh, J-S. Woo, G-S. Im, S. Hwang. (2017) Effects of cell cycle regulators on the cell cycle synchronization of porcine induced pluripotent stem cells. Dev. Reprod., 21 (1), 47-54.
21. S-C. Lee, H. Lee, K. Oh, I-S. Hwang, H. Yang, M-R. Park, S-A. Ock, J-S. Woo, G-S. Im, S. Hwang. (2017) Production of breeding of transgenic cloned pigs expressing human CD73. Dev. Reprod., 21 (2), 157-165.
22. I-S. Hwang, S. Lee, S. Kim, D-J. Kwon, M-R. Park, H. Yang, K. Oh, S. Ock, J-S. Woo, G-S. Im, S. Hwang. (2017) Analysis of semen parameters in α1,3-galactosyltransferase^-/- boars. J. Emb. Trans., 32 (2), 53-58.
23. S. Kim, M. Ki, C-L. Kim, I-S. Hwang, I. Jeon. (2017) A simple confocal microscopy-based method for assessing sperm movement. Dev. Reprod., 21 (3), 229-235.
24. S-W. Kim, N. Sharma, I-S. Hwang, C. Choe, D. Kim, H-H. Seong, D-K. Jeong. (2017) Application of saponin on differential staining examination in animal blastocysts. Indian J. Anim. Sci., 87 (9), 1081-1086.
25. W-S. Sun, J-L. Chun, D-H. Kim, J-S. Ahn, M-K. Kim, I-S. Hwang, D-J. Kwon, S. Hwang, J-W. Lee. (2017) Molecular cloning and characterization of the porcine ribosomal protein L21. J. Vet. Sci., 18 (4), 531-540.
26. I-S. Hwang, M-R. Park, T-U. Kwak, S-H. Park, J-H. Lim, S. Kim, S. Hwang. (2018) Effect of cytochalasin B treatment on the improvement of survival rate in vitrified pig oocyte. Dev. Reprod., 22 (3), 245-252.
27. J-G. No, S-J. Byun, H. Yang, S. Ock, J-S. Woo, H-C. Lee, I-S. Hwang, J-Y. Kim, S-H. Park, J-Y. Lee, K. Oh. (2018) Development of aortic endothelial cells to express CD37 and CD73 isolated from alpha 1,3-galactosyltransferase knock-out and MCP expressing pig. J. Emb. Trans., 33 (3), 129-137.
28. D-J. Kwon, J-D. Oh, M-R. Park, I-S. Hwang, E-W. Park, S. Hwang. (2019) Developmental characteristics of cloned embryos reconstructed with induced pluripotent stem cells in pigs. J. Anim. Reprod. Biotechnol., 34 (3), 232-239.
29. I-C. Cho, H-B. Park, J. Ahn, S-H. Han, J-B. Lee, H-T. Lim, C-K. Yoo, E-J. Jung, D-H. Kim, W-S. Sun, Y. Ramayo-Caldas, S-G. Kim, Y-J. Kang, Y-K. Kim, H-S. Shin, P-N. Seong, I-S. Hwang, B-Y. Park, S. Hwang, S-S. Lee, Y-C. Ryu, J-H. Lee, M-S. Ko, K. Lee, G. Andersson, M. Pérez-Enciso, J-W. Lee. (2019) A functional regulatory variant of MYH3 influences muscle fiber-type composition and intramuscular fat content in pigs. PLoS Genet., 15 (10), e1008279.
30. M-R. Park, I-S. Hwang, T-U. Kwak, J-H. Lim, S. Hwang, S-K. Cho. (2020) Low expression of mitofusin 1 is associated with mitochondrial dysfunction and apoptosis in porcine somatic cell nuclear transfer embryos. Anim. Sci. J., 91 (1), e13430.
31. H. Lee, I-S. Hwang, B.M.K. Vasamsetti, H.R. Rallabandi, M-R. Park, S-J. Byun, H. Yang, S. Ock, H-C. Lee, J-S. Woo, S. Hwang, K. Oh. (2020) Codon optimized membrane cofactor protein expression in α1,3 galactosyltransferase knockout pig cells improve protection against cytotoxicity of monkey serum. 3 Biotech, 10 (3), 108.
32. J. Ahn, H. Wu, J. Lee, I-S. Hwang, D. Yu, J-S. Ahn, J-W. Lee, S. Hwang, K. Lee. (2020) Identification of a novel imprinted transcript in the porcine GNAS complex locus using methylome and transcriptome of parthenogenetic fetuses. Genes, 11 (1), 96.
33. I-S. Hwang, M-R. Park, H-S. Lee, T-U. Kwak, H-Y. Son, J-K. Kang, J-W. Lee, K. Lee, E-W. Park, S. Hwang. (2020) Developmental and degenerative characterization of porcine parthenogenetic fetuses during early pregnancy. Animals, 10 (4), 622.
34. W-S. Sun, H. Jang, H. Kwon, K. Kim, S. Ahn, S. Hwang, S. Lee, J. Lee, I-S. Hwang, J-W. Lee. (2020) The protective effect of Leucosporidium-derived ice-binding protein (LeIBP) on bovine oocytes and embryos during vitrification. Theriogenology, 151, 137-143.
35. H. Jang, H. Kwon, W. Sun, S. Hwang, I-S. Hwang, S. Kim, J. Lee, S. Lee, J. Lee. (2020) Effects of Leucosporidium-derived ice-binding protein (LeIBP) on bull semen cryopreservation. Vet. Med. Sci., 6 (3), 447-453.
36. J. Ahn, I-S. Hwang, M-R. Park, I-C. Cho, S. Hwang, K. Lee. (2020) The landscape of genomic imprinting at the porcine SGCE/PEG10 locus from methylome and transcriptome of parthenogenetic embryos. G3: Gene, Genomes, Genetics, 10 (11), 4037-4047.
37. S. Kim, J-Y. Lee, B. Kim, C-L. Kim, I-S. Hwang, Y-G. Ko, S-S. Lee. (2020) Ultrasonic cutting of frozen semen straws to optimize the use of spermatozoa for in vitro fertilization. Animals, 10 (11), 2152.
38. S-W. Kim, Y-G. Ko, J-Y. Lee, C-L. Kim, I-S. Hwang. (2020) The use of styrofoam box for Chikso (Korean brindled cattle) semen cryopreservation with liquid nitrogen. J. Korea Academia-Industrial Coop. Soc., 21 (4) 490-496.
39. J. Yun, I-S. Hwang, S. Hwang, M-R. Park. (2020) Characterization of TRAF4 mRNA and function related to tight junction in pig. J. Korea Academia-Industrial Coop. Soc., 21 (5) 216-222.
40. M-R. Park, I-S. Hwang, S. Lee, H-C. Lee. (2020) Comparison of hematologic and biochemical values in htPA transgenic pigs. J. Korea Academia-Industrial Coop. Soc., 21 (12) 395-400.
41. M. Park, B.M.K. Vasamsetti, W. Kim, H. Kang, D-Y. Kim, B. Lim, K. Cho, J. Kim, H. Chee, J. Park, H. Yang, H.R. Rallabandi, S. Ock, M-R. Park, H. Lee, I-S. Hwang, J-M. Kim, K. Oh, I. Yun. (2021) Comprehensive analysis of cardiac xeno-graft unveils rejection mechanisms. Int. J. Mol. Sci., 22 (2), 751.
42. J. Ahn, I-S. Hwang, M-R. Park, I-C. Cho, S. Hwang, K. Lee. (2021) Genomic imprinting at the porcine PLAGL1 locus and the orthologous locus in the human. Genes, 12 (4), 541.
43. J. Ahn, I-S. Hwang, M-R. Park, S. Hwang, K. Lee. (2021) Genomic imprinting at the porcine DIRAS3 locus. Animals, 11 (5), 1315.
44. W-S. Sun, H. Jang, M-R. Park, K. Oh, H. Lee, S. Hwang, L-J. Xu, I-S. Hwang, J-W. Lee. (2021) N-acetyl-L-cysteine improves the developmental competence of bovine oocytes and embryos cultured in vitro by attenuating oxidative damage and apoptosis. Antioxidants, 10 (6), 860.
45. J.G. No, H. Lee, N.H. Kee, W-S. Sun, I-S. Hwang, M. Lee, K.B. Oh. (2021) Porcine tissue factor promoter induces specific expression of target gene in response to human serum in porcine aortic endothelial cells. Korean J. Agric. Sci., 48 (2), 353-365.
46. I-S. Hwang, J. Shim, K. Oh, H. Lee, M-R. Park. (2022) cd26 knockdown negatively affects porcine parthenogenetic preimplantation embryo development. Animals, 12 (13), 1662.
47. I-S. Hwang. (2022) Fertility preservation in pig using ovarian tissues by vitrification method. J. Anim. Reprod. Biotechnol., 37 (2), 106-112.
48. K-R. Park, H. Yang, H. Wi, S. Ock, P. Lee, I-S. Hwang, B-R. Lee. (2022) Effect of Wnt signaling pathway activation on the efficient generation of bovine intestinal organoids. J. Anim. Reprod. Biotechnol., 37 (2), 136-143.
49. J. Ahn, J. Lee, D-H. Kim, I-S. Hwang, M-R. Park, I-C. Cho, S. Hwang, K. Lee. (2022) Loss of monoallelic expression of IGF2 in the adult liver via alternative promoter usage and chromatin reorganization. Front. Genet., 13, 920641.
50. K-W. Park, H. Yang, M-G. Lee, S. Ock, H. Wi, P. Lee, I-S. Hwang, J-G. Yoo, C-K. Park, B-R. Lee. (2022) Establishment of intestinal organoids from small intestine of growing cattle (12 months old). J. Anim. Sci. Technol., 64 (6), 1105-1116.
51. J. Ahn, I-S. Hwang, M-R. Park, S. Hwang, K. Lee. (2023) Imprinting at the KBTBD6 locus involves species-specific maternal methylation and monoallelic expression in livestock animals. J. Anim. Sci. Biotechnol., 14 (1), 131.
52. J. Ahn, I-S. Hwang, M-R. Park, S. Hwang, I-C. Cho, K. Lee. (2023) The AIRN IncRNA is imprinted and paternally expressed in pigs. J. Anim. Sci., 101, skad367.
53. M-R. Park, J. Ahn, M. Lee, B. Lee, S. Ock, S. Byun, I-S. Hwang. (2023) Characterization of enlarged tongues in cloned piglets. Curr. Issues Mol. Biol., 45 (11), 9103-9116.
54. J. Ahn, I-S. Hwang, M-R. Park, M.R. Velazquez, I-C. Cho, A.E. Relling, S. Hwang, K. Lee. (2024) Lineage-specific genomic imprinting in the ZNF791 locus. (bioRxiv preprint, posted July 16, 2024)